School of Medicine

Wayne State University School of Medicine

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Akm A. Sattar, Ph.D.
Assistant Professor
University Health Center - 4H
4201 St. Antoine
Detroit, MI 48201
Biography

Education:

  • B.S., Biochemistry, Dhaka University, Dhaka, Bangladesh 1982
  • M.S., Biochemistry, Dhaka University, Dhaka, Bangladesh 1985
  • Ph.D., Pharmaceutical Science, Nagasaki University, Nagasaki, Japan 1990
  • Postdoc., Molecular Biology & Biochemistry, Yale University School of Medicine, New Haven, CT 1990-1994

Positions and Honors:

  • 1985 Research Associate in Nutritional Biochemistry, Dhaka University, Dhaka, Bangladesh
  • 1986 Lecturer in Nutritional Biochemistry, Dhaka University, Dhaka, Bangladesh
  • 1986-1987 Research Fellow in Pharmaceutical Science, Nagasaki University, Nagasaki, Japan
  • 1990-1994 Postdoctoral Associate, Yale University School of Medicine, New Haven, CT
  • 1994-2000 Associate Research Scientist, Yale University School of Medicine, New Haven, CT
  • 2000-Present Assistant Professor, Wayne State University School of Medicine, Detroit, MI

Honors & Specific Recognition:

  • 1983-1984 Post-graduate Diploma Award in Nutrition, INFS, Dhaka University, Dhaka, Bangladesh
  • 1986-1990 Monbusho Shogakkin, Japan Government Scholarship for Higher Studies
  • Reviewer: Manuscript-reviewer for Medical Education Online
Peer-Reviewed Publications

1. Majumder, M.S.I, Sattar, A.A, and Zaman, N. “Effect of vitamin A deficiency on guineapig Payer’s patches.” Nutrition Research 7, 539-545 (1987)

2. Majumder, M.S.I and Sattar, A.A. “Payer’s patches immune function of vitamin A deficient guineapigs. ” Nutrition Reports International 36, 143-150 (1987)

3. Yoshimoto, T., Sattar, A.A., Hirose, W., and Tsuru, D. “Studies on prolyl endopeptidase from carrot (Daucus carota): purification and enzymatic properties.” Biochem. Biophys. Acta 916, 29-37 (1987)

4. Yoshimoto, T., Sattar, A.A., Hirose, W., and Tsuru, D. “Studies on prolyl endopeptidase from shakashimeji (Lyophyllum cinerascen): purification and enzymatic properties.” J. Biochem. 104, 622-627 (1988)

5. Yoshimoto, T., Matsuo, F., Oyama, H., Honda, T., Sattar, A.A., and Tsuru, D. “Purification and characterization of prolyl endopeptidase from Flavobacterium breve.” Biochem. (Life Sci. Adv.) 7, 313- 316 (1988)

6. Sattar, A.A., Yoshimoto, T., and Tsuru, D. “Lyophillum cinerascens aminopeptidase: purification and enzymatic properties.” Arch. Biochem. Biophys. 274, 241-250 (1989)

7. Sattar, A.A., Yoshimoto, T., and Tsuru, D. “Purification and characterization of proline iminopeptidase from Lyophillum cinerascens.” J. Ferment. Bioeng. 68, 178-182 (1989)

8. Sattar, A.A., Yamamoto, N., Yoshimoto, T., and Tsuru, D. “Purification and characterization of an extracellular prolyl endopeptidase from Agaricus bisporus.” J. Biochem. 107, 256-261 (1990)

9. O’Mally, S.M., Sattar, A., William, K.R., and Spicer, E.K. “Mutagenesis of the COOH-terminal region of bacteriophage T4 regA protein.” J. Biol. Chem. 270, 5107-5114 (1995)

10. Sattar, A.A., Lin, T.C., Jones, C., and Konigsberg, W.H. “Functional consequences and exonuclease kinetic parameters of point mutations of bacteriophage T4 DNA polymerase.” Biochemistry 35, 16621-16629 (1996)

11. Wang, J., Sattar, A.A., Wang, C.C., Karam, J.D., Konigsberg, W.H., and Steitz, T.A. “Crystal structure of a pol alpha family replication DNA polymerase from bacteriophage RB69.” Cell 89, 1087-1099 (1997)

12. Jeong, E-H., Webster, P., Khuong, C.Q., Sattar, A.A., Satchi, M., and Jena, B.P. “The native membrane fusion machinery in cells.” Cell Biology International 9110, 657-670 (1998)

13. Cho, S.J, Sattar, A.A., Jeong, E-H., Satchi, M., Cho, J.A., Das, S., Mayes, M.S., Stromer, M.H., and Jena, B.P “Aquaporin 1 regulates GTP-Induced rapid gating of water in secretory vesicles.” Proc. Natl. Acad. Sci. U.S.A. 99, 4720-4724 (2002)

14. Sattar, A.A., Boinpally, R., Stromer, M., and Jena, B.P. “Gαi3 in pancreatic zymogen granules participates in vesicular fusion.” J. Biochem. 131, 815 -820 (2002)

15. Sattar, A.A., and Haque, R. “Cytosolic PLA2 in zymogen granule fusion and amylase release: inhibition of GTP-induced fusion by arachidonyl trifluoromethyl ketone points to cPLA2 in G-Protein Mediated Secretory Vesicle Fusion.” Journal of Biochemistry 2006; doi: 10.1093/jb/mvm007(Just published)

16. Sattar, A.A., Berhanu, C., Gebreselassie, S., and Berhanu, P. “Human insulin receptor juxtamembrane domain independent insulin signaling.” Cell Biology International 2007; doi: 10. 1016/j.cellbi.2007.01.033

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Abstracts

1. Sattar, A.A. and Berhanu, P. “Intracellular trafficking of the human insulin receptor requires the intact juxtamembrane domain segment but not its specific amino acid sequence: Dependence of trafficking on PI-3 and MAP kinases.” Diabetes (Supplement 1) 54, P. A623-A624 (2005)

2. Sattar, A.A. and Berhanu, P. “Human Insulin Receptor (hIR) and Glucose Transporter (GLUT4) Trafficking in Transfected CHO Cells: Effects of the Inhibitors of PI-3 and MAP Kinases and that of the Actin-Microtubules” Mol. Biol. Cell 17 (Supplement) CD-Rom (2006)